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Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513
MicroRNAs (miRNAs) are small post-transcriptional regulators that offer promising targets for treating complex diseases. To this end, hsa-miR-4513 is an excellent candidate as this gene harbors within its conserved heptametrical seed sequence a frequent polymorphism (rs2168518), which has previously...
Autores principales: | Kiel, Christina, Strunz, Tobias, Hasler, Daniele, Meister, Gunter, Grassmann, Felix, Weber, Bernhard H F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947236/ https://www.ncbi.nlm.nih.gov/pubmed/34605899 http://dx.doi.org/10.1093/hmg/ddab292 |
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