Optimizing the Timing of Highest Hydrocortisone Dose in Children and Adolescents With 21-Hydroxylase Deficiency

CONTEXT: Hydrocortisone treatment of young patients with 21-hydroxylase deficiency (21OHD) is given thrice daily, but there is debate about the optimal timing of the highest hydrocortisone dose, either mimicking the physiological diurnal rhythm (morning), or optimally suppressing androgen activity (...

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Detalles Bibliográficos
Autores principales: Schröder, Mariska A M, van Herwaarden, Antonius E, Span, Paul N, van den Akker, Erica L T, Bocca, Gianni, Hannema, Sabine E, van der Kamp, Hetty J, de Kort, Sandra W K, Mooij, Christiaan F, Schott, Dina A, Straetemans, Saartje, van Tellingen, Vera, van der Velden, Janiëlle A, Sweep, Fred C G J, Claahsen-van der Grinten, Hedi L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947312/
https://www.ncbi.nlm.nih.gov/pubmed/34788830
http://dx.doi.org/10.1210/clinem/dgab826

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