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Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947342/ https://www.ncbi.nlm.nih.gov/pubmed/35327883 http://dx.doi.org/10.3390/e24030372 |
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author | Almeida, Ricardo Agarwal, Ravi P. Hristova, Snezhana O’Regan, Donal |
author_facet | Almeida, Ricardo Agarwal, Ravi P. Hristova, Snezhana O’Regan, Donal |
author_sort | Almeida, Ricardo |
collection | PubMed |
description | A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional order systems and the advantage of quadratic functions are pointed out. The equilibrium of the generalized proportional Caputo fractional model and its generalized exponential stability are defined, and sufficient conditions for the generalized exponential stability and asymptotic stability of the equilibrium are obtained. As a special case, the stability of the equilibrium of the Caputo fractional model is discussed. Several examples are provided to illustrate our theoretical results and the influence of the type of fractional derivative on the stability behavior of the equilibrium. |
format | Online Article Text |
id | pubmed-8947342 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89473422022-03-25 Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations Almeida, Ricardo Agarwal, Ravi P. Hristova, Snezhana O’Regan, Donal Entropy (Basel) Article A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional order systems and the advantage of quadratic functions are pointed out. The equilibrium of the generalized proportional Caputo fractional model and its generalized exponential stability are defined, and sufficient conditions for the generalized exponential stability and asymptotic stability of the equilibrium are obtained. As a special case, the stability of the equilibrium of the Caputo fractional model is discussed. Several examples are provided to illustrate our theoretical results and the influence of the type of fractional derivative on the stability behavior of the equilibrium. MDPI 2022-03-05 /pmc/articles/PMC8947342/ /pubmed/35327883 http://dx.doi.org/10.3390/e24030372 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Almeida, Ricardo Agarwal, Ravi P. Hristova, Snezhana O’Regan, Donal Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title | Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title_full | Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title_fullStr | Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title_full_unstemmed | Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title_short | Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations |
title_sort | stability of gene regulatory networks modeled by generalized proportional caputo fractional differential equations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947342/ https://www.ncbi.nlm.nih.gov/pubmed/35327883 http://dx.doi.org/10.3390/e24030372 |
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