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Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations

A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional o...

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Detalles Bibliográficos
Autores principales: Almeida, Ricardo, Agarwal, Ravi P., Hristova, Snezhana, O’Regan, Donal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947342/
https://www.ncbi.nlm.nih.gov/pubmed/35327883
http://dx.doi.org/10.3390/e24030372
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author Almeida, Ricardo
Agarwal, Ravi P.
Hristova, Snezhana
O’Regan, Donal
author_facet Almeida, Ricardo
Agarwal, Ravi P.
Hristova, Snezhana
O’Regan, Donal
author_sort Almeida, Ricardo
collection PubMed
description A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional order systems and the advantage of quadratic functions are pointed out. The equilibrium of the generalized proportional Caputo fractional model and its generalized exponential stability are defined, and sufficient conditions for the generalized exponential stability and asymptotic stability of the equilibrium are obtained. As a special case, the stability of the equilibrium of the Caputo fractional model is discussed. Several examples are provided to illustrate our theoretical results and the influence of the type of fractional derivative on the stability behavior of the equilibrium.
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spelling pubmed-89473422022-03-25 Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations Almeida, Ricardo Agarwal, Ravi P. Hristova, Snezhana O’Regan, Donal Entropy (Basel) Article A model of gene regulatory networks with generalized proportional Caputo fractional derivatives is set up, and stability properties are studied. Initially, some properties of absolute value Lyapunov functions and quadratic Lyapunov functions are discussed, and also, their application to fractional order systems and the advantage of quadratic functions are pointed out. The equilibrium of the generalized proportional Caputo fractional model and its generalized exponential stability are defined, and sufficient conditions for the generalized exponential stability and asymptotic stability of the equilibrium are obtained. As a special case, the stability of the equilibrium of the Caputo fractional model is discussed. Several examples are provided to illustrate our theoretical results and the influence of the type of fractional derivative on the stability behavior of the equilibrium. MDPI 2022-03-05 /pmc/articles/PMC8947342/ /pubmed/35327883 http://dx.doi.org/10.3390/e24030372 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Almeida, Ricardo
Agarwal, Ravi P.
Hristova, Snezhana
O’Regan, Donal
Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title_full Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title_fullStr Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title_full_unstemmed Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title_short Stability of Gene Regulatory Networks Modeled by Generalized Proportional Caputo Fractional Differential Equations
title_sort stability of gene regulatory networks modeled by generalized proportional caputo fractional differential equations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947342/
https://www.ncbi.nlm.nih.gov/pubmed/35327883
http://dx.doi.org/10.3390/e24030372
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