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Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock

BACKGROUND: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is controversial as a hemorrhage control adjunct due to lack of data with a suitable control group. We aimed to determine outcomes of trauma patients in shock undergoing REBOA versus no-REBOA. METHODS: This single-center,...

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Autores principales: Harfouche, Melike N., Madurska, Marta J., Elansary, Noha, Abdou, Hossam, Lang, Eric, DuBose, Joseph J., Kundi, Rishi, Feliciano, David V., Scalea, Thomas M., Morrison, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947416/
https://www.ncbi.nlm.nih.gov/pubmed/35324991
http://dx.doi.org/10.1371/journal.pone.0265778
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author Harfouche, Melike N.
Madurska, Marta J.
Elansary, Noha
Abdou, Hossam
Lang, Eric
DuBose, Joseph J.
Kundi, Rishi
Feliciano, David V.
Scalea, Thomas M.
Morrison, Jonathan J.
author_facet Harfouche, Melike N.
Madurska, Marta J.
Elansary, Noha
Abdou, Hossam
Lang, Eric
DuBose, Joseph J.
Kundi, Rishi
Feliciano, David V.
Scalea, Thomas M.
Morrison, Jonathan J.
author_sort Harfouche, Melike N.
collection PubMed
description BACKGROUND: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is controversial as a hemorrhage control adjunct due to lack of data with a suitable control group. We aimed to determine outcomes of trauma patients in shock undergoing REBOA versus no-REBOA. METHODS: This single-center, retrospective, matched cohort study analyzed patients ≥16 years in hemorrhagic shock without cardiac arrest (2000–2019). REBOA (R; 2015–2019) patients were propensity matched 2:1 to historic (H; 2000–2012) and contemporary (C; 2013–2019) groups. In-hospital mortality and 30-day survival were analyzed using chi-squared and log rank testing, respectively. RESULTS: A total of 102,481 patients were included (R = 57, C = 88,545, H = 13,879). Propensity scores were assigned using age, race, mechanism, lowest systolic blood pressure, lowest Glasgow Coma Score (GCS), and body region Abbreviated Injury Scale scores to generate matched groups (R = 57, C = 114, H = 114). In-hospital mortality was significantly lower in the REBOA group (19.3%) compared to the contemporary (35.1%; p = 0.024) and historic (44.7%; p = 0.001) groups. 30-day survival was significantly higher in the REBOA versus no-REBOA groups. CONCLUSION: In a high-volume center where its use is part of a coordinated hemorrhage control strategy, REBOA is associated with improved survival in patients with noncompressible torso hemorrhage.
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spelling pubmed-89474162022-03-25 Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock Harfouche, Melike N. Madurska, Marta J. Elansary, Noha Abdou, Hossam Lang, Eric DuBose, Joseph J. Kundi, Rishi Feliciano, David V. Scalea, Thomas M. Morrison, Jonathan J. PLoS One Research Article BACKGROUND: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is controversial as a hemorrhage control adjunct due to lack of data with a suitable control group. We aimed to determine outcomes of trauma patients in shock undergoing REBOA versus no-REBOA. METHODS: This single-center, retrospective, matched cohort study analyzed patients ≥16 years in hemorrhagic shock without cardiac arrest (2000–2019). REBOA (R; 2015–2019) patients were propensity matched 2:1 to historic (H; 2000–2012) and contemporary (C; 2013–2019) groups. In-hospital mortality and 30-day survival were analyzed using chi-squared and log rank testing, respectively. RESULTS: A total of 102,481 patients were included (R = 57, C = 88,545, H = 13,879). Propensity scores were assigned using age, race, mechanism, lowest systolic blood pressure, lowest Glasgow Coma Score (GCS), and body region Abbreviated Injury Scale scores to generate matched groups (R = 57, C = 114, H = 114). In-hospital mortality was significantly lower in the REBOA group (19.3%) compared to the contemporary (35.1%; p = 0.024) and historic (44.7%; p = 0.001) groups. 30-day survival was significantly higher in the REBOA versus no-REBOA groups. CONCLUSION: In a high-volume center where its use is part of a coordinated hemorrhage control strategy, REBOA is associated with improved survival in patients with noncompressible torso hemorrhage. Public Library of Science 2022-03-24 /pmc/articles/PMC8947416/ /pubmed/35324991 http://dx.doi.org/10.1371/journal.pone.0265778 Text en © 2022 Harfouche et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Harfouche, Melike N.
Madurska, Marta J.
Elansary, Noha
Abdou, Hossam
Lang, Eric
DuBose, Joseph J.
Kundi, Rishi
Feliciano, David V.
Scalea, Thomas M.
Morrison, Jonathan J.
Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title_full Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title_fullStr Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title_full_unstemmed Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title_short Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
title_sort resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947416/
https://www.ncbi.nlm.nih.gov/pubmed/35324991
http://dx.doi.org/10.1371/journal.pone.0265778
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