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Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma

It is essential to accurately and safely resect all tumors during surgery for multiple lung metastases. Here, we report a case of hepatoblastoma (HB) with multiple pulmonary nodules that ultimately underwent complete resection using combined three-dimensional image reconstruction and indocyanine gre...

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Autores principales: Komatsu, Shugo, Terui, Keita, Nakata, Mitsuyuki, Shibata, Ryohei, Oita, Satoru, Kawaguchi, Yunosuke, Yoshizawa, Hiroko, Hirokawa, Tomoya, Nakatani, Erika, Hishiki, Tomoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947451/
https://www.ncbi.nlm.nih.gov/pubmed/35327748
http://dx.doi.org/10.3390/children9030376
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author Komatsu, Shugo
Terui, Keita
Nakata, Mitsuyuki
Shibata, Ryohei
Oita, Satoru
Kawaguchi, Yunosuke
Yoshizawa, Hiroko
Hirokawa, Tomoya
Nakatani, Erika
Hishiki, Tomoro
author_facet Komatsu, Shugo
Terui, Keita
Nakata, Mitsuyuki
Shibata, Ryohei
Oita, Satoru
Kawaguchi, Yunosuke
Yoshizawa, Hiroko
Hirokawa, Tomoya
Nakatani, Erika
Hishiki, Tomoro
author_sort Komatsu, Shugo
collection PubMed
description It is essential to accurately and safely resect all tumors during surgery for multiple lung metastases. Here, we report a case of hepatoblastoma (HB) with multiple pulmonary nodules that ultimately underwent complete resection using combined three-dimensional image reconstruction and indocyanine green (ICG) fluorescence guidance. A 1-year-old boy was diagnosed with HB and multiple lung metastases. After intensive chemotherapy, complete resection with subsegmentectomy (S5 + 6) and partial resection (S3, S8) were performed. More than 100 pulmonary nodules, which remained visible on computed tomography (CT) despite additional postoperative chemotherapy, were subjected to pulmonary resection. We used the SYNAPSE VINCENT software (Fujifilm Medical, Tokyo, Japan) to obtain three-dimensional images of the nodules. We numbered each nodule, and 33 lesions of the right lung were resected by multiple wedge resections through a right thoracotomy, with the aid of palpation and ICG fluorescence guidance. One month after the right metastasectomy, resection of 64 lesions in the left lung was performed via left thoracotomy. Postoperative CT showed complete clearance of the lung lesions, and the patient remained disease-free for 15 months after the treatment. This case study confirms that the combination of three-dimensional localization and ICG fluorescence guidance allows for accurate and safe resection of nearly 100 lung metastases.
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spelling pubmed-89474512022-03-25 Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma Komatsu, Shugo Terui, Keita Nakata, Mitsuyuki Shibata, Ryohei Oita, Satoru Kawaguchi, Yunosuke Yoshizawa, Hiroko Hirokawa, Tomoya Nakatani, Erika Hishiki, Tomoro Children (Basel) Case Report It is essential to accurately and safely resect all tumors during surgery for multiple lung metastases. Here, we report a case of hepatoblastoma (HB) with multiple pulmonary nodules that ultimately underwent complete resection using combined three-dimensional image reconstruction and indocyanine green (ICG) fluorescence guidance. A 1-year-old boy was diagnosed with HB and multiple lung metastases. After intensive chemotherapy, complete resection with subsegmentectomy (S5 + 6) and partial resection (S3, S8) were performed. More than 100 pulmonary nodules, which remained visible on computed tomography (CT) despite additional postoperative chemotherapy, were subjected to pulmonary resection. We used the SYNAPSE VINCENT software (Fujifilm Medical, Tokyo, Japan) to obtain three-dimensional images of the nodules. We numbered each nodule, and 33 lesions of the right lung were resected by multiple wedge resections through a right thoracotomy, with the aid of palpation and ICG fluorescence guidance. One month after the right metastasectomy, resection of 64 lesions in the left lung was performed via left thoracotomy. Postoperative CT showed complete clearance of the lung lesions, and the patient remained disease-free for 15 months after the treatment. This case study confirms that the combination of three-dimensional localization and ICG fluorescence guidance allows for accurate and safe resection of nearly 100 lung metastases. MDPI 2022-03-08 /pmc/articles/PMC8947451/ /pubmed/35327748 http://dx.doi.org/10.3390/children9030376 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Komatsu, Shugo
Terui, Keita
Nakata, Mitsuyuki
Shibata, Ryohei
Oita, Satoru
Kawaguchi, Yunosuke
Yoshizawa, Hiroko
Hirokawa, Tomoya
Nakatani, Erika
Hishiki, Tomoro
Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title_full Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title_fullStr Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title_full_unstemmed Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title_short Combined Use of Three-Dimensional Construction and Indocyanine Green-Fluorescent Imaging for Resection of Multiple Lung Metastases in Hepatoblastoma
title_sort combined use of three-dimensional construction and indocyanine green-fluorescent imaging for resection of multiple lung metastases in hepatoblastoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947451/
https://www.ncbi.nlm.nih.gov/pubmed/35327748
http://dx.doi.org/10.3390/children9030376
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