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Nonparametric Causal Structure Learning in High Dimensions

The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown t...

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Autores principales: Chakraborty, Shubhadeep, Shojaie, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947566/
https://www.ncbi.nlm.nih.gov/pubmed/35327862
http://dx.doi.org/10.3390/e24030351
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author Chakraborty, Shubhadeep
Shojaie, Ali
author_facet Chakraborty, Shubhadeep
Shojaie, Ali
author_sort Chakraborty, Shubhadeep
collection PubMed
description The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown to be consistent for learning sparse high-dimensional DAGs based on partial correlations. However, inferring conditional independences from partial correlations is valid if the data are jointly Gaussian or generated from a linear structural equation model—an assumption that may be violated in many applications. To broaden the scope of high-dimensional causal structure learning, we propose nonparametric variants of the PC-stable and FCI-stable algorithms that employ the conditional distance covariance (CdCov) to test for conditional independence relationships. As the key theoretical contribution, we prove that the high-dimensional consistency of the PC-stable and FCI-stable algorithms carry over to general distributions over DAGs when we implement CdCov-based nonparametric tests for conditional independence. Numerical studies demonstrate that our proposed algorithms perform nearly as good as the PC-stable and FCI-stable for Gaussian distributions, and offer advantages in non-Gaussian graphical models.
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spelling pubmed-89475662022-03-25 Nonparametric Causal Structure Learning in High Dimensions Chakraborty, Shubhadeep Shojaie, Ali Entropy (Basel) Article The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown to be consistent for learning sparse high-dimensional DAGs based on partial correlations. However, inferring conditional independences from partial correlations is valid if the data are jointly Gaussian or generated from a linear structural equation model—an assumption that may be violated in many applications. To broaden the scope of high-dimensional causal structure learning, we propose nonparametric variants of the PC-stable and FCI-stable algorithms that employ the conditional distance covariance (CdCov) to test for conditional independence relationships. As the key theoretical contribution, we prove that the high-dimensional consistency of the PC-stable and FCI-stable algorithms carry over to general distributions over DAGs when we implement CdCov-based nonparametric tests for conditional independence. Numerical studies demonstrate that our proposed algorithms perform nearly as good as the PC-stable and FCI-stable for Gaussian distributions, and offer advantages in non-Gaussian graphical models. MDPI 2022-02-28 /pmc/articles/PMC8947566/ /pubmed/35327862 http://dx.doi.org/10.3390/e24030351 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chakraborty, Shubhadeep
Shojaie, Ali
Nonparametric Causal Structure Learning in High Dimensions
title Nonparametric Causal Structure Learning in High Dimensions
title_full Nonparametric Causal Structure Learning in High Dimensions
title_fullStr Nonparametric Causal Structure Learning in High Dimensions
title_full_unstemmed Nonparametric Causal Structure Learning in High Dimensions
title_short Nonparametric Causal Structure Learning in High Dimensions
title_sort nonparametric causal structure learning in high dimensions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947566/
https://www.ncbi.nlm.nih.gov/pubmed/35327862
http://dx.doi.org/10.3390/e24030351
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