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Nonparametric Causal Structure Learning in High Dimensions
The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947566/ https://www.ncbi.nlm.nih.gov/pubmed/35327862 http://dx.doi.org/10.3390/e24030351 |
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author | Chakraborty, Shubhadeep Shojaie, Ali |
author_facet | Chakraborty, Shubhadeep Shojaie, Ali |
author_sort | Chakraborty, Shubhadeep |
collection | PubMed |
description | The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown to be consistent for learning sparse high-dimensional DAGs based on partial correlations. However, inferring conditional independences from partial correlations is valid if the data are jointly Gaussian or generated from a linear structural equation model—an assumption that may be violated in many applications. To broaden the scope of high-dimensional causal structure learning, we propose nonparametric variants of the PC-stable and FCI-stable algorithms that employ the conditional distance covariance (CdCov) to test for conditional independence relationships. As the key theoretical contribution, we prove that the high-dimensional consistency of the PC-stable and FCI-stable algorithms carry over to general distributions over DAGs when we implement CdCov-based nonparametric tests for conditional independence. Numerical studies demonstrate that our proposed algorithms perform nearly as good as the PC-stable and FCI-stable for Gaussian distributions, and offer advantages in non-Gaussian graphical models. |
format | Online Article Text |
id | pubmed-8947566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89475662022-03-25 Nonparametric Causal Structure Learning in High Dimensions Chakraborty, Shubhadeep Shojaie, Ali Entropy (Basel) Article The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown to be consistent for learning sparse high-dimensional DAGs based on partial correlations. However, inferring conditional independences from partial correlations is valid if the data are jointly Gaussian or generated from a linear structural equation model—an assumption that may be violated in many applications. To broaden the scope of high-dimensional causal structure learning, we propose nonparametric variants of the PC-stable and FCI-stable algorithms that employ the conditional distance covariance (CdCov) to test for conditional independence relationships. As the key theoretical contribution, we prove that the high-dimensional consistency of the PC-stable and FCI-stable algorithms carry over to general distributions over DAGs when we implement CdCov-based nonparametric tests for conditional independence. Numerical studies demonstrate that our proposed algorithms perform nearly as good as the PC-stable and FCI-stable for Gaussian distributions, and offer advantages in non-Gaussian graphical models. MDPI 2022-02-28 /pmc/articles/PMC8947566/ /pubmed/35327862 http://dx.doi.org/10.3390/e24030351 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chakraborty, Shubhadeep Shojaie, Ali Nonparametric Causal Structure Learning in High Dimensions |
title | Nonparametric Causal Structure Learning in High Dimensions |
title_full | Nonparametric Causal Structure Learning in High Dimensions |
title_fullStr | Nonparametric Causal Structure Learning in High Dimensions |
title_full_unstemmed | Nonparametric Causal Structure Learning in High Dimensions |
title_short | Nonparametric Causal Structure Learning in High Dimensions |
title_sort | nonparametric causal structure learning in high dimensions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947566/ https://www.ncbi.nlm.nih.gov/pubmed/35327862 http://dx.doi.org/10.3390/e24030351 |
work_keys_str_mv | AT chakrabortyshubhadeep nonparametriccausalstructurelearninginhighdimensions AT shojaieali nonparametriccausalstructurelearninginhighdimensions |