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Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management
The role of 2-deoxy-2-[(18)F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) in the management of prostate cancer (PCa) patients is increasingly recognised. However, its clinical role is still controversial. Many published studies showed that FDG PET/CT might have a pr...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947589/ https://www.ncbi.nlm.nih.gov/pubmed/35328134 http://dx.doi.org/10.3390/diagnostics12030581 |
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author | Borea, Roberto Favero, Diletta Miceli, Alberto Donegani, Maria Isabella Raffa, Stefano Gandini, Annalice Cremante, Malvina Marini, Cecilia Sambuceti, Gianmario Zanardi, Elisa Morbelli, Silvia Fornarini, Giuseppe Rebuzzi, Sara Elena Bauckneht, Matteo |
author_facet | Borea, Roberto Favero, Diletta Miceli, Alberto Donegani, Maria Isabella Raffa, Stefano Gandini, Annalice Cremante, Malvina Marini, Cecilia Sambuceti, Gianmario Zanardi, Elisa Morbelli, Silvia Fornarini, Giuseppe Rebuzzi, Sara Elena Bauckneht, Matteo |
author_sort | Borea, Roberto |
collection | PubMed |
description | The role of 2-deoxy-2-[(18)F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) in the management of prostate cancer (PCa) patients is increasingly recognised. However, its clinical role is still controversial. Many published studies showed that FDG PET/CT might have a prognostic value in the metastatic castration-resistant phase of the disease, but its role in other settings of PCa and, more importantly, its impact on final clinical management remains to be further investigated. We describe a series of six representative clinical cases of PCa in different clinical settings, but all characterised by a measurable clinical impact of FDG PET/CT on the patients’ management. Starting from their clinical history, we report a concise narrative literature review on the advantages and limitations of FDG PET/CT beyond its prognostic value in PCa. What emerges is that in selected cases, this imaging technique may represent a useful tool in managing PCa patients. However, in the absence of dedicated studies to define the optimal clinical setting of its application, no standard recommendations on its use in PCa patients can be made. |
format | Online Article Text |
id | pubmed-8947589 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89475892022-03-25 Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management Borea, Roberto Favero, Diletta Miceli, Alberto Donegani, Maria Isabella Raffa, Stefano Gandini, Annalice Cremante, Malvina Marini, Cecilia Sambuceti, Gianmario Zanardi, Elisa Morbelli, Silvia Fornarini, Giuseppe Rebuzzi, Sara Elena Bauckneht, Matteo Diagnostics (Basel) Review The role of 2-deoxy-2-[(18)F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) in the management of prostate cancer (PCa) patients is increasingly recognised. However, its clinical role is still controversial. Many published studies showed that FDG PET/CT might have a prognostic value in the metastatic castration-resistant phase of the disease, but its role in other settings of PCa and, more importantly, its impact on final clinical management remains to be further investigated. We describe a series of six representative clinical cases of PCa in different clinical settings, but all characterised by a measurable clinical impact of FDG PET/CT on the patients’ management. Starting from their clinical history, we report a concise narrative literature review on the advantages and limitations of FDG PET/CT beyond its prognostic value in PCa. What emerges is that in selected cases, this imaging technique may represent a useful tool in managing PCa patients. However, in the absence of dedicated studies to define the optimal clinical setting of its application, no standard recommendations on its use in PCa patients can be made. MDPI 2022-02-24 /pmc/articles/PMC8947589/ /pubmed/35328134 http://dx.doi.org/10.3390/diagnostics12030581 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Borea, Roberto Favero, Diletta Miceli, Alberto Donegani, Maria Isabella Raffa, Stefano Gandini, Annalice Cremante, Malvina Marini, Cecilia Sambuceti, Gianmario Zanardi, Elisa Morbelli, Silvia Fornarini, Giuseppe Rebuzzi, Sara Elena Bauckneht, Matteo Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title | Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title_full | Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title_fullStr | Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title_full_unstemmed | Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title_short | Beyond the Prognostic Value of 2-[(18)F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management |
title_sort | beyond the prognostic value of 2-[(18)f]fdg pet/ct in prostate cancer: a case series and literature review focusing on the diagnostic value and impact on patient management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947589/ https://www.ncbi.nlm.nih.gov/pubmed/35328134 http://dx.doi.org/10.3390/diagnostics12030581 |
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