HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities

Shotgun metagenomics is a powerful tool to identify antimicrobial resistance (AMR) genes in microbiomes but has the limitation that extrachromosomal DNA, such as plasmids, cannot be linked with the host bacterial chromosome. Here we present a comprehensive laboratory and bioinformatics pipeline HAM-...

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Detalles Bibliográficos
Autores principales: Kalmar, Lajos, Gupta, Srishti, Kean, Iain R. L., Ba, Xiaoliang, Hadjirin, Nazreen, Lay, Elizabeth M., de Vries, Stefan P. W., Bateman, Michael, Bartlet, Harriet, Hernandez-Garcia, Juan, Tucker, Alexander W., Restif, Olivier, Stevens, Mark P., Wood, James L. N., Maskell, Duncan J., Grant, Andrew J., Holmes, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947609/
https://www.ncbi.nlm.nih.gov/pubmed/35286304
http://dx.doi.org/10.1371/journal.pgen.1009776

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