Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer

Aberrant DNA methylation is an early event in breast carcinogenesis and plays a critical role in regulating gene expression. Here, we perform genome-wide expression-methylation Quantitative Trait Loci (emQTL) analysis through the integration of DNA methylation and gene expression to identify disease...

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Detalles Bibliográficos
Autores principales: Ankill, Jørgen, Aure, Miriam Ragle, Bjørklund, Sunniva, Langberg, Severin, Kristensen, Vessela N, Vitelli, Valeria, Tekpli, Xavier, Fleischer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947789/
https://www.ncbi.nlm.nih.gov/pubmed/35350772
http://dx.doi.org/10.1093/narcan/zcac008

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