Salvianolic Acid B Suppresses ER Stress-Induced NLRP3 Inflammasome and Pyroptosis via the AMPK/FoxO4 and Syndecan-4/Rac1 Signaling Pathways in Human Endothelial Progenitor Cells

Mounting evidence demonstrates uncontrolled endoplasmic reticulum (ER) stress responses can activate the inflammasome, which generally results in endothelial dysfunction, a major pathogenetic factor of chronic inflammatory diseases such as atherosclerosis. Salvianolic acid B (SalB), produced by Radi...

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Detalles Bibliográficos
Autores principales: Tang, Yubo, Wa, Qingde, Peng, Longyun, Zheng, Yifan, Chen, Jie, Chen, Xiao, Zou, Xuenong, Shen, Huangxuan, Huang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947883/
https://www.ncbi.nlm.nih.gov/pubmed/35340217
http://dx.doi.org/10.1155/2022/8332825

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