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Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica
This study was aimed to investigate the craniocerebral magnetic resonance imaging (MRI) measurement and clinical characteristics of patients with neuromyelitis optica (NMO) and multiple sclerosis (MS). 50 patients with NMO (NMO group) and 50 patients with MS (MS group) were studied. The clinical man...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947891/ https://www.ncbi.nlm.nih.gov/pubmed/35360267 http://dx.doi.org/10.1155/2022/1430380 |
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author | Lu, Shujuan Wang, Dongming Zhang, Fengxian Liu, Meilan |
author_facet | Lu, Shujuan Wang, Dongming Zhang, Fengxian Liu, Meilan |
author_sort | Lu, Shujuan |
collection | PubMed |
description | This study was aimed to investigate the craniocerebral magnetic resonance imaging (MRI) measurement and clinical characteristics of patients with neuromyelitis optica (NMO) and multiple sclerosis (MS). 50 patients with NMO (NMO group) and 50 patients with MS (MS group) were studied. The clinical manifestations, brain injury morphology, MRI signal characteristics, brain distribution characteristics, and related laboratory tests (serum aquaporin 4 [AQP4] antibody) were statistically analyzed. The results showed that the analysis of clinical manifestations of patients revealed that optic neuritis (37 cases) was the most common disease in NMO patients, and myelitis (16 cases) was more common in MS patients than NMO patients. There were significant differences in gender ratio, abnormal expression of brain MR1, positive serum AQP4-IgG, and other immune diseases and symptoms between the two groups (P < 0.05). When the lesions measured by MRI were located in the white matter area of the cerebral hemisphere, the image showed blurred edges and a relatively symmetrical distribution. When the lesions measured by MRI were located around the medulla oblongata, the lesions mainly involved the central gray matter and white matter of the spinal cord, with patchy and line-like long T1 and long T2 signals. Moreover, in the late stage of recurrence of spinal cord disease, severe spinal cord atrophy may occur. In conclusion, craniocerebral MRI measurement in NMO patients can provide more basis for the diagnosis and differential diagnosis of the disease, so as to improve the diagnostic level of NMO. |
format | Online Article Text |
id | pubmed-8947891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-89478912022-03-30 Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica Lu, Shujuan Wang, Dongming Zhang, Fengxian Liu, Meilan Contrast Media Mol Imaging Research Article This study was aimed to investigate the craniocerebral magnetic resonance imaging (MRI) measurement and clinical characteristics of patients with neuromyelitis optica (NMO) and multiple sclerosis (MS). 50 patients with NMO (NMO group) and 50 patients with MS (MS group) were studied. The clinical manifestations, brain injury morphology, MRI signal characteristics, brain distribution characteristics, and related laboratory tests (serum aquaporin 4 [AQP4] antibody) were statistically analyzed. The results showed that the analysis of clinical manifestations of patients revealed that optic neuritis (37 cases) was the most common disease in NMO patients, and myelitis (16 cases) was more common in MS patients than NMO patients. There were significant differences in gender ratio, abnormal expression of brain MR1, positive serum AQP4-IgG, and other immune diseases and symptoms between the two groups (P < 0.05). When the lesions measured by MRI were located in the white matter area of the cerebral hemisphere, the image showed blurred edges and a relatively symmetrical distribution. When the lesions measured by MRI were located around the medulla oblongata, the lesions mainly involved the central gray matter and white matter of the spinal cord, with patchy and line-like long T1 and long T2 signals. Moreover, in the late stage of recurrence of spinal cord disease, severe spinal cord atrophy may occur. In conclusion, craniocerebral MRI measurement in NMO patients can provide more basis for the diagnosis and differential diagnosis of the disease, so as to improve the diagnostic level of NMO. Hindawi 2022-03-17 /pmc/articles/PMC8947891/ /pubmed/35360267 http://dx.doi.org/10.1155/2022/1430380 Text en Copyright © 2022 Shujuan Lu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lu, Shujuan Wang, Dongming Zhang, Fengxian Liu, Meilan Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title | Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title_full | Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title_fullStr | Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title_full_unstemmed | Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title_short | Magnetic Resonance Image in Monitor and Diagnosis of Patients with Neuromyelitis Optica |
title_sort | magnetic resonance image in monitor and diagnosis of patients with neuromyelitis optica |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947891/ https://www.ncbi.nlm.nih.gov/pubmed/35360267 http://dx.doi.org/10.1155/2022/1430380 |
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