Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types

Due to activation of fibroblast into cancer-associated fibroblasts, there is often an increased deposition of extracellular matrix and fibrillar collagens, e.g. type III collagen, in the tumor microenvironment (TME) that leads to tumor fibrosis (desmoplasia). Tumor fibrosis is closely associated wit...

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Detalles Bibliográficos
Autores principales: Willumsen, Nicholas, Jensen, Christina, Green, George, Nissen, Neel I., Neely, Jaclyn, Nelson, David M., Pedersen, Rasmus S., Frederiksen, Peder, Chen, Inna M., Boisen, Mogens K., Johansen, Astrid Z., Madsen, Daniel H., Svane, Inge Marie, Lipton, Allan, Leitzel, Kim, Ali, Suhail M., Erler, Janine T., Hurkmans, Daan P., Mathijssen, Ron H. J., Aerts, Joachim, Eslam, Mohammed, George, Jacob, Christiansen, Claus, Bissel, Mina J., Karsdal, Morten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948122/
https://www.ncbi.nlm.nih.gov/pubmed/35332383
http://dx.doi.org/10.1007/s00018-022-04226-0

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