Accounting for age of onset and family history improves power in genome-wide association studies

Genome-wide association studies (GWASs) have revolutionized human genetics, allowing researchers to identify thousands of disease-related genes and possible drug targets. However, case-control status does not account for the fact that not all controls may have lived through their period of risk for...

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Detalles Bibliográficos
Autores principales: Pedersen, Emil M., Agerbo, Esben, Plana-Ripoll, Oleguer, Grove, Jakob, Dreier, Julie W., Musliner, Katherine L., Bækvad-Hansen, Marie, Athanasiadis, Georgios, Schork, Andrew, Bybjerg-Grauholm, Jonas, Hougaard, David M., Werge, Thomas, Nordentoft, Merete, Mors, Ole, Dalsgaard, Søren, Christensen, Jakob, Børglum, Anders D., Mortensen, Preben B., McGrath, John J., Privé, Florian, Vilhjálmsson, Bjarni J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948165/
https://www.ncbi.nlm.nih.gov/pubmed/35139346
http://dx.doi.org/10.1016/j.ajhg.2022.01.009

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