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AXL inhibition improves BRAF-targeted treatment in melanoma
More than half of metastatic melanoma patients receiving standard therapy fail to achieve a long-term survival due to primary and/or acquired resistance. Tumor cell ability to switch from epithelial to a more aggressive mesenchymal phenotype, attributed with AXL(high) molecular profile in melanoma,...
Autores principales: | Nyakas, Marta, Fleten, Karianne Giller, Haugen, Mads Haugland, Engedal, Nikolai, Sveen, Christina, Farstad, Inger Nina, Flørenes, Vivi Ann, Prasmickaite, Lina, Mælandsmo, Gunhild Mari, Seip, Kotryna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948193/ https://www.ncbi.nlm.nih.gov/pubmed/35332208 http://dx.doi.org/10.1038/s41598-022-09078-z |
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