Notch signaling pathway: architecture, disease, and therapeutics

The NOTCH gene was identified approximately 110 years ago. Classical studies have revealed that NOTCH signaling is an evolutionarily conserved pathway. NOTCH receptors undergo three cleavages and translocate into the nucleus to regulate the transcription of target genes. NOTCH signaling deeply parti...

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Detalles Bibliográficos
Autores principales: Zhou, Binghan, Lin, Wanling, Long, Yaling, Yang, Yunkai, Zhang, Huan, Wu, Kongming, Chu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948217/
https://www.ncbi.nlm.nih.gov/pubmed/35332121
http://dx.doi.org/10.1038/s41392-022-00934-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948217/
https://www.ncbi.nlm.nih.gov/pubmed/35332121
http://dx.doi.org/10.1038/s41392-022-00934-y

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