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Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics

Hematopoietic stem cells (HSCs) develop from hemogenic endothelium within embryonic arterial vessels such as the aorta of the aorta-gonad-mesonephros region (AGM). To identify the signals responsible for HSC formation, here we use single cell RNA-sequencing to simultaneously analyze the transcriptio...

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Detalles Bibliográficos
Autores principales:	Hadland, Brandon, Varnum-Finney, Barbara, Dozono, Stacey, Dignum, Tessa, Nourigat-McKay, Cynthia, Heck, Adam M., Ishida, Takashi, Jackson, Dana L., Itkin, Tomer, Butler, Jason M., Rafii, Shahin, Trapnell, Cole, Bernstein, Irwin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948249/ https://www.ncbi.nlm.nih.gov/pubmed/35332125 http://dx.doi.org/10.1038/s41467-022-28781-z

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