Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation

Glycolytic and mitochondrial oxidative metabolism, which are two major energy sources in tumors, are potential targets in cancer treatment. Metabolic reprogramming from glycolysis to mitochondrial oxidative metabolism and vice versa is an adaptive strategy with which tumor cells obtain energy to sur...

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Detalles Bibliográficos
Autores principales: Cheng, Gang, Hardy, Micael, You, Ming, Kalyanaraman, Balaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948292/
https://www.ncbi.nlm.nih.gov/pubmed/35332210
http://dx.doi.org/10.1038/s41598-022-08984-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948292/
https://www.ncbi.nlm.nih.gov/pubmed/35332210
http://dx.doi.org/10.1038/s41598-022-08984-6

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