Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)

High‐Throughput Screening of Combinatorial Drugs In article number 2104449, Peng Shi, Honglin Li, Xudong Lin, and co‐workers develop a novel fish capsules (FC) system, that is based on an automated zebrafish encapsulating technology and a microdroplet array strategy, to enable large‐scale immobiliza...

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Detalles Bibliográficos
Autores principales: Tang, Minghui, Duan, Xin, Yang, Anqi, He, Shijie, Zhou, Yajing, Liu, Yuxin, Zhang, Lu, Luo, Xuan, Shi, Peng, Li, Honglin, Lin, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948553/
http://dx.doi.org/10.1002/advs.202270056
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author Tang, Minghui
Duan, Xin
Yang, Anqi
He, Shijie
Zhou, Yajing
Liu, Yuxin
Zhang, Lu
Luo, Xuan
Shi, Peng
Li, Honglin
Lin, Xudong
author_facet Tang, Minghui
Duan, Xin
Yang, Anqi
He, Shijie
Zhou, Yajing
Liu, Yuxin
Zhang, Lu
Luo, Xuan
Shi, Peng
Li, Honglin
Lin, Xudong
author_sort Tang, Minghui
collection PubMed
description High‐Throughput Screening of Combinatorial Drugs In article number 2104449, Peng Shi, Honglin Li, Xudong Lin, and co‐workers develop a novel fish capsules (FC) system, that is based on an automated zebrafish encapsulating technology and a microdroplet array strategy, to enable large‐scale immobilization of oriented zebrafish larvae and compound parallel addition. Coupling with bioinformatic analysis and machine learning algorithms, this system is successfully demonstrated for in vivo high‐throughput functional screening of mono/poly‐therapies. [Image: see text]
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spelling pubmed-89485532022-03-29 Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022) Tang, Minghui Duan, Xin Yang, Anqi He, Shijie Zhou, Yajing Liu, Yuxin Zhang, Lu Luo, Xuan Shi, Peng Li, Honglin Lin, Xudong Adv Sci (Weinh) Frontispiece High‐Throughput Screening of Combinatorial Drugs In article number 2104449, Peng Shi, Honglin Li, Xudong Lin, and co‐workers develop a novel fish capsules (FC) system, that is based on an automated zebrafish encapsulating technology and a microdroplet array strategy, to enable large‐scale immobilization of oriented zebrafish larvae and compound parallel addition. Coupling with bioinformatic analysis and machine learning algorithms, this system is successfully demonstrated for in vivo high‐throughput functional screening of mono/poly‐therapies. [Image: see text] John Wiley and Sons Inc. 2022-03-25 /pmc/articles/PMC8948553/ http://dx.doi.org/10.1002/advs.202270056 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Frontispiece
Tang, Minghui
Duan, Xin
Yang, Anqi
He, Shijie
Zhou, Yajing
Liu, Yuxin
Zhang, Lu
Luo, Xuan
Shi, Peng
Li, Honglin
Lin, Xudong
Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title_full Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title_fullStr Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title_full_unstemmed Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title_short Fish Capsules: A System for High‐Throughput Screening of Combinatorial Drugs (Adv. Sci. 9/2022)
title_sort fish capsules: a system for high‐throughput screening of combinatorial drugs (adv. sci. 9/2022)
topic Frontispiece
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948553/
http://dx.doi.org/10.1002/advs.202270056
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