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3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells

Understanding the effects induced by carcinogens on primary colonic epithelial cells and how to counteract them might help to prevent colon cancer, which is one of the most frequent and aggressive cancers. In this study, we exposed primary human colonic epithelial cells (HCoEpC) to Benzo[a]pyrene (B...

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Detalles Bibliográficos
Autores principales:	Santarelli, Roberta, Pompili, Chiara, Gilardini Montani, Maria Saveria, Evangelista, Lorenzo, Gonnella, Roberta, Cirone, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948646/ https://www.ncbi.nlm.nih.gov/pubmed/35336037 http://dx.doi.org/10.3390/pharmaceutics14030663

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