Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma

It has been previously shown that (never in mitosis gene A)‐related kinase 2 (NEK2) is upregulated in multiple myeloma (MM) and contributes to drug resistance. However, the mechanisms behind this upregulation remain poorly understood. In this study, it is found that amplification of NEK2 and hyperme...

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Detalles Bibliográficos
Autores principales: Feng, Xiangling, Guo, Jiaojiao, An, Gang, Wu, Yangbowen, Liu, Zhenhao, Meng, Bin, He, Nihan, Zhao, Xinying, Chen, Shilian, Zhu, Yinghong, Xia, Jiliang, Li, Xin, Yu, Zhiyong, Li, Ruixuan, Ren, Guofeng, Chen, Jihua, Wu, Minghua, He, Yanjuan, Qiu, Lugui, Zhou, Jiaxi, Zhou, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948659/
https://www.ncbi.nlm.nih.gov/pubmed/35088582
http://dx.doi.org/10.1002/advs.202104491

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