Reducing the Excess Activin Signaling Rescues Muscle Degeneration in Myotonic Dystrophy Type 2 Drosophila Model

Expanded non-coding RNA repeats of CCUG are the underlying genetic causes for myotonic dystrophy type 2 (DM2). There is an urgent need for effective medications and potential drug targets that may alleviate the progression of the disease. In this study, 3140 small-molecule drugs from FDA-approved li...

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Detalles Bibliográficos
Autores principales: Deng, Jing, Guan, Xin-Xin, Zhu, Ying-Bao, Deng, Hai-Tao, Li, Guang-Xu, Guo, Yi-Chen, Jin, Peng, Duan, Ran-Hui, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948895/
https://www.ncbi.nlm.nih.gov/pubmed/35330385
http://dx.doi.org/10.3390/jpm12030385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948895/
https://www.ncbi.nlm.nih.gov/pubmed/35330385
http://dx.doi.org/10.3390/jpm12030385

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