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Effect of Intersection Angle of Input Channels in Droplet Generators
In this paper, we studied the effects of the intersection angle between the inlet channels on the droplet diameter using a COMSOL Multiphysics(®) simulation. We employed the level-set method to study the droplet generation process inside a microfluidic flow device. A flow-focusing geometry was integ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948941/ https://www.ncbi.nlm.nih.gov/pubmed/35335156 http://dx.doi.org/10.3390/molecules27061791 |
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author | Kim, Gi-Beum Park, Young-Ran Kim, Seong-Jong Park, Kwang-Hyun |
author_facet | Kim, Gi-Beum Park, Young-Ran Kim, Seong-Jong Park, Kwang-Hyun |
author_sort | Kim, Gi-Beum |
collection | PubMed |
description | In this paper, we studied the effects of the intersection angle between the inlet channels on the droplet diameter using a COMSOL Multiphysics(®) simulation. We employed the level-set method to study the droplet generation process inside a microfluidic flow device. A flow-focusing geometry was integrated into a microfluidics device and used to study droplet formation in liquid–liquid systems. Droplets formed by this flow-focusing technique are typically smaller than the upstream capillary tube and vary in size with the flow rates. Different intersection angles were modeled with a fixed width of continuous and dispersed channels, orifices, and expansion channels. Numerical simulations were performed using the incompressible Navier–Stokes equations for single-phase flow in various flow-focusing geometries. As a result of modeling, when the dispersed flow rate and the continuous flow rate were increased, the flow of the continuous flow fluid interfered with the flow of the dispersed flow fluid, which resulted in a decrease in the droplet diameter. Variations in the droplet diameter can be used to change the intersection angle and fluid flow rate. In addition, it was predicted that the smallest diameter droplet would be generated when the intersection angle was 90°. |
format | Online Article Text |
id | pubmed-8948941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89489412022-03-26 Effect of Intersection Angle of Input Channels in Droplet Generators Kim, Gi-Beum Park, Young-Ran Kim, Seong-Jong Park, Kwang-Hyun Molecules Article In this paper, we studied the effects of the intersection angle between the inlet channels on the droplet diameter using a COMSOL Multiphysics(®) simulation. We employed the level-set method to study the droplet generation process inside a microfluidic flow device. A flow-focusing geometry was integrated into a microfluidics device and used to study droplet formation in liquid–liquid systems. Droplets formed by this flow-focusing technique are typically smaller than the upstream capillary tube and vary in size with the flow rates. Different intersection angles were modeled with a fixed width of continuous and dispersed channels, orifices, and expansion channels. Numerical simulations were performed using the incompressible Navier–Stokes equations for single-phase flow in various flow-focusing geometries. As a result of modeling, when the dispersed flow rate and the continuous flow rate were increased, the flow of the continuous flow fluid interfered with the flow of the dispersed flow fluid, which resulted in a decrease in the droplet diameter. Variations in the droplet diameter can be used to change the intersection angle and fluid flow rate. In addition, it was predicted that the smallest diameter droplet would be generated when the intersection angle was 90°. MDPI 2022-03-09 /pmc/articles/PMC8948941/ /pubmed/35335156 http://dx.doi.org/10.3390/molecules27061791 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kim, Gi-Beum Park, Young-Ran Kim, Seong-Jong Park, Kwang-Hyun Effect of Intersection Angle of Input Channels in Droplet Generators |
title | Effect of Intersection Angle of Input Channels in Droplet Generators |
title_full | Effect of Intersection Angle of Input Channels in Droplet Generators |
title_fullStr | Effect of Intersection Angle of Input Channels in Droplet Generators |
title_full_unstemmed | Effect of Intersection Angle of Input Channels in Droplet Generators |
title_short | Effect of Intersection Angle of Input Channels in Droplet Generators |
title_sort | effect of intersection angle of input channels in droplet generators |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948941/ https://www.ncbi.nlm.nih.gov/pubmed/35335156 http://dx.doi.org/10.3390/molecules27061791 |
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