Cargando…
Activation of Autophagy by Low-Dose Silica Nanoparticles Enhances Testosterone Secretion in Leydig Cells
Silica nanoparticles (SNPs) can cause abnormal spermatogenesis in male reproductive toxicity. However, the toxicity and toxicological mechanisms of SNPs in testosterone synthesis and secretion in Leydig cells are not well known. Therefore, this study aimed to determine the effect and molecular mecha...
Autores principales: | Zhang, Jinlong, Ye, Rongrong, Grunberger, Jason William, Jin, Jiaqi, Zhang, Qianru, Mohammadpour, Raziye, Khurana, Nitish, Xu, Xianyu, Ghandehari, Hamidreza, Chen, Fenglei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949068/ https://www.ncbi.nlm.nih.gov/pubmed/35328525 http://dx.doi.org/10.3390/ijms23063104 |
Ejemplares similares
-
BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells
por: Zhang, Qianru, et al.
Publicado: (2022) -
Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction
por: Zheng, Zhen, et al.
Publicado: (2023) -
Sex-Specific
Silica Nanoparticle Protein Corona Compositions
Exposed to Male and Female BALB/c Mice Plasmas
por: Ashkarran, Ali Akbar, et al.
Publicado: (2022) -
Layer-by-Layer Hollow Mesoporous Silica Nanoparticles with Tunable Degradation Profile
por: Grunberger, Jason William, et al.
Publicado: (2023) -
Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells
por: Gao, Fengyi, et al.
Publicado: (2018)