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Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19

Background: Malnutrition has been linked to adverse health economic outcomes. There is a paucity of data on malnutrition in patients admitted with COVID-19. Methods: This is a retrospective cohort study consisting of 4311 COVID-19 adult (18 years and older) inpatients at 5 Johns Hopkins-affiliated h...

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Autores principales: Vong, Tyrus, Yanek, Lisa R., Wang, Lin, Yu, Huimin, Fan, Christopher, Zhou, Elinor, Oh, Sun Jung, Szvarca, Daniel, Kim, Ahyoung, Potter, James J., Mullin, Gerard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949069/
https://www.ncbi.nlm.nih.gov/pubmed/35334967
http://dx.doi.org/10.3390/nu14061310
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author Vong, Tyrus
Yanek, Lisa R.
Wang, Lin
Yu, Huimin
Fan, Christopher
Zhou, Elinor
Oh, Sun Jung
Szvarca, Daniel
Kim, Ahyoung
Potter, James J.
Mullin, Gerard E.
author_facet Vong, Tyrus
Yanek, Lisa R.
Wang, Lin
Yu, Huimin
Fan, Christopher
Zhou, Elinor
Oh, Sun Jung
Szvarca, Daniel
Kim, Ahyoung
Potter, James J.
Mullin, Gerard E.
author_sort Vong, Tyrus
collection PubMed
description Background: Malnutrition has been linked to adverse health economic outcomes. There is a paucity of data on malnutrition in patients admitted with COVID-19. Methods: This is a retrospective cohort study consisting of 4311 COVID-19 adult (18 years and older) inpatients at 5 Johns Hopkins-affiliated hospitals between 1 March and 3 December 2020. Malnourishment was identified using the malnutrition universal screening tool (MUST), then confirmed by registered dietitians. Statistics were conducted with SAS v9.4 (Cary, NC, USA) software to examine the effect of malnutrition on mortality and hospital length of stay among COVID-19 inpatient encounters, while accounting for possible covariates in regression analysis predicting mortality or the log-transformed length of stay. Results: COVID-19 patients who were older, male, or had lower BMIs had a higher likelihood of mortality. Patients with malnutrition were 76% more likely to have mortality (p < 0.001) and to have a 105% longer hospital length of stay (p < 0.001). Overall, 12.9% (555/4311) of adult COVID-19 patients were diagnosed with malnutrition and were associated with an 87.9% increase in hospital length of stay (p < 0.001). Conclusions: In a cohort of COVID-19 adult inpatients, malnutrition was associated with a higher likelihood of mortality and increased hospital length of stay.
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spelling pubmed-89490692022-03-26 Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19 Vong, Tyrus Yanek, Lisa R. Wang, Lin Yu, Huimin Fan, Christopher Zhou, Elinor Oh, Sun Jung Szvarca, Daniel Kim, Ahyoung Potter, James J. Mullin, Gerard E. Nutrients Article Background: Malnutrition has been linked to adverse health economic outcomes. There is a paucity of data on malnutrition in patients admitted with COVID-19. Methods: This is a retrospective cohort study consisting of 4311 COVID-19 adult (18 years and older) inpatients at 5 Johns Hopkins-affiliated hospitals between 1 March and 3 December 2020. Malnourishment was identified using the malnutrition universal screening tool (MUST), then confirmed by registered dietitians. Statistics were conducted with SAS v9.4 (Cary, NC, USA) software to examine the effect of malnutrition on mortality and hospital length of stay among COVID-19 inpatient encounters, while accounting for possible covariates in regression analysis predicting mortality or the log-transformed length of stay. Results: COVID-19 patients who were older, male, or had lower BMIs had a higher likelihood of mortality. Patients with malnutrition were 76% more likely to have mortality (p < 0.001) and to have a 105% longer hospital length of stay (p < 0.001). Overall, 12.9% (555/4311) of adult COVID-19 patients were diagnosed with malnutrition and were associated with an 87.9% increase in hospital length of stay (p < 0.001). Conclusions: In a cohort of COVID-19 adult inpatients, malnutrition was associated with a higher likelihood of mortality and increased hospital length of stay. MDPI 2022-03-21 /pmc/articles/PMC8949069/ /pubmed/35334967 http://dx.doi.org/10.3390/nu14061310 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vong, Tyrus
Yanek, Lisa R.
Wang, Lin
Yu, Huimin
Fan, Christopher
Zhou, Elinor
Oh, Sun Jung
Szvarca, Daniel
Kim, Ahyoung
Potter, James J.
Mullin, Gerard E.
Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title_full Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title_fullStr Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title_full_unstemmed Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title_short Malnutrition Increases Hospital Length of Stay and Mortality among Adult Inpatients with COVID-19
title_sort malnutrition increases hospital length of stay and mortality among adult inpatients with covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949069/
https://www.ncbi.nlm.nih.gov/pubmed/35334967
http://dx.doi.org/10.3390/nu14061310
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