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Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model Episkin(TM): Perspectives for Application as Potential Sunscreen Agents
This study aimed to assess two novel 5-arylideneimidazolidine-2,4-dione (hydantoin) derivatives (JH3 and JH10) demonstrating photoprotective activity using the reconstructed human skin model Episkin(TM). The skin permeability, irritation, and phototoxicity of the compounds was evaluated in vitro. Mo...
Autores principales: | Słoczyńska, Karolina, Popiół, Justyna, Gunia-Krzyżak, Agnieszka, Koczurkiewicz-Adamczyk, Paulina, Żmudzki, Paweł, Pękala, Elżbieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949075/ https://www.ncbi.nlm.nih.gov/pubmed/35335215 http://dx.doi.org/10.3390/molecules27061850 |
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