Cargando…

Plant-Derived Antiviral Compounds as Potential Entry Inhibitors against Spike Protein of SARS-CoV-2 Wild-Type and Delta Variant: An Integrative in SilicoApproach

The wild-type SARS-CoV-2 has continuously evolved into several variants with increased transmissibility and virulence. The Delta variant which was initially identified in India created a devastating impact throughout the country during the second wave. While the efficacy of the existing vaccines aga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ambrose, Jenifer Mallavarpu, Kullappan, Malathi, Patil, Shankargouda, Alzahrani, Khalid J., Banjer, Hamsa Jameel, Qashqari, Fadi S. I., Raj, A. Thirumal, Bhandi, Shilpa, Veeraraghavan, Vishnu Priya, Jayaraman, Selvaraj, Sekar, Durairaj, Agarwal, Alok, Swapnavahini, Korla, Krishna Mohan, Surapaneni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949152/ https://www.ncbi.nlm.nih.gov/pubmed/35335139 http://dx.doi.org/10.3390/molecules27061773

Ejemplares similares

Repurposing of potential antiviral drugs against RNA-dependent RNA polymerase of SARS-CoV-2 by computational approach
por: Gangadharan, Sivakumar, et al.
Publicado: (2022)

Comparison of Immunological Profiles of SARS-CoV-2 Variants in the COVID-19 Pandemic Trends: An Immunoinformatics Approach
por: Mallavarpu Ambrose, Jenifer, et al.
Publicado: (2021)

Structure-Based Virtual Screening of Benzaldehyde Thiosemicarbazone Derivatives against DNA Gyrase B of Mycobacterium tuberculosis
por: Kistan, Andiyappan, et al.
Publicado: (2021)

Ellagic Acid as a Potential Inhibitor against the Nonstructural Protein NS3 Helicase of Zika Virus: A Molecular Modelling Study
por: Kullappan, Malathi, et al.
Publicado: (2022)

Dose-Dependent Effects of Melatonin on the Viability, Proliferation, and Differentiation of Dental Pulp Stem Cells (DPSCs)
por: Patil, Shankargouda, et al.
Publicado: (2022)

Polysaccharide-Drug Conjugates: A Tool for Enhanced Cancer Therapy
por: Yadav, Neena, et al.
Publicado: (2022)

Receptor binding domain of SARS‐CoV‐2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2
por: Patil, Shankargouda, et al.
Publicado: (2022)

Molecular docking data of E3 ubiquitin-protein ligase WWP1 with compounds from a medicinal plant Justicia adhatoda L
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Molecular docking of alkaloid compounds with the matrix metalloproteinase 2
por: Fathima, JH Shazia, et al.
Publicado: (2021)

Molecular docking analysis of SARS-CoV-2 linked RNA dependent RNA polymerase (RdRp) with compounds from Plectranthus amboinicus
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Molecular modeling of cornulin (CRNN) for docking with phytocompounds from Justicia adhatoda L.
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Molecular docking of potential inhibitors with the mTOR protein
por: Fathima, JH Shazia, et al.
Publicado: (2021)

Impact of Red Complex Bacteria and TNF-α Levels on the Diabetic and Renal Status of Chronic Kidney Disease Patients in the Presence and Absence of Periodontitis
por: Mahendra, Jaideep, et al.
Publicado: (2022)

Deciphering the Role of MicroRNAs in Neuroblastoma
por: Veeraraghavan, Vishnu Priya, et al.
Publicado: (2021)

An Overview on the Therapeutic Function of Foods Enriched with Plant Sterols in Diabetes Management
por: Jayaraman, Selvaraj, et al.
Publicado: (2021)

Eleven Crucial Pesticides Appear to Regulate Key Genes That Link MPTP Mechanism to Cause Parkinson’s Disease through the Selective Degeneration of Dopamine Neurons
por: Anirudhan, Athira, et al.
Publicado: (2023)

Multi-target potential of Indian phytochemicals against SARS-CoV-2: A docking, molecular dynamics and MM-GBSA approach extended to Omicron B.1.1.529.
por: Roshni, Jency, et al.
Publicado: (2022)

Molecular docking analysis of phytocompounds from Andrographis paniculata binding with proteins in the notch-signaling pathway
por: Deiva Suga, Sumetha Suga, et al.
Publicado: (2020)

Impact of meteorological factors and population density on COVID-19 pandemic in Saudi Arabia
por: Alzahrani, Khalid J., et al.
Publicado: (2023)

Genomic surveillance, evolution and global transmission of SARS-CoV-2 during 2019–2022
por: Sharif, Nadim, et al.
Publicado: (2022)

Evaluation of Candidiasis in Upper-Aerodigestive Squamous Cell Carcinoma Patients—A Clinico-Mycological Aspect
por: Debta, Priyanka, et al.
Publicado: (2022)

A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach
por: Prasad, Monisha, et al.
Publicado: (2022)

Molecular docking analysis of imiquimod with the TGF-β targets for oral carcinoma
por: Pazhani, Jayanthi, et al.
Publicado: (2023)

Molecular docking analysis of cetuximab with NOTCH signalling pathway targets for oral cancer
por: Pazhani, Jayanthi, et al.
Publicado: (2023)

Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
por: Pazhani, Jayanthi, et al.
Publicado: (2023)

Therapeutic implication of chimeric antigen receptor T-cell therapy for head and neck squamous cell carcinoma
por: Pazhani, Jayanthi, et al.
Publicado: (2023)

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer
por: Preethi, K. Auxzilia, et al.
Publicado: (2022)

Inflammation in smokers and non-smokers during implant surgery among Indians
por: EP, Raguladhithya, et al.
Publicado: (2023)

Ensemble Deep-Learning-Based Prognostic and Prediction for Recurrence of Sporadic Odontogenic Keratocysts on Hematoxylin and Eosin Stained Pathological Images of Incisional Biopsies
por: Rao, Roopa S., et al.
Publicado: (2022)

Awareness and knowledge of oral manifestations in cardiovascular diseases among the general public
por: Shreenidhi, S., et al.
Publicado: (2022)

Effect of Different Intracanal Medicaments on the Viability and Survival of Dental Pulp Stem Cells
por: Bhandi, Shilpa, et al.
Publicado: (2022)

Knowledge on cervical cancer and perceived barriers to the uptake of HPV vaccination among health professionals
por: Chellapandian, Poongodi, et al.
Publicado: (2021)

Unveiling the anti-cancer mechanisms of calotropin: Insights into cell growth inhibition, cell cycle arrest, and metabolic regulation in human oral squamous carcinoma cells (HSC-3)
por: Jayaraman, Selvaraj, et al.
Publicado: (2023)

Docking analysis of importin-11 homology model with the phyto compounds towards colorectal cancer treatment
por: Selvaraj, Jayaraman, et al.
Publicado: (2020)

Antioxidant effects of Emblica officinalis and Zingiber officinalis on arsenic and lead induced toxicity on Albino rats
por: Fazal, Mohd, et al.
Publicado: (2021)

Pleiotropic effects of DCLK1 in cancer and cancer stem cells
por: Chhetri, Dibyashree, et al.
Publicado: (2022)

Seroprevalence of Hepatitis E Virus Infection in Middle Eastern Countries: A Systematic Review and Meta-Analysis
por: Qashqari, Fadi S.
Publicado: (2022)

Molecular docking analysis of alkaloid compounds with beta-catenin towards the treatment of colon cancer
por: Ponnulakshmi, Rajagopal, et al.
Publicado: (2020)

Identification of miR-802-5p and its involvement in type 2 diabetes mellitus
por: Rajkumar, Kaushik Vishnu, et al.
Publicado: (2020)

Role of Toothbrushes as Gene Expression Profiling Tool for Oral Cancer Screening in Tobacco and Alcohol Users
por: Sujatha, Govindarajan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nert7ti9601v16rp2gmp6uenhl