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p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin

Chemotherapeutic drug-induced p53-dependent crosstalk among tumor cells affects the sensitivity of tumor cells to chemotherapeutic drugs, contributing to chemoresistance. Therefore, pharmacological targeting of p53 may contribute to overcoming drug resistance. The localization of p53 is closely rela...

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Detalles Bibliográficos
Autores principales: Kong, Qinghuan, Yan, Xiaoyu, Cheng, Meiyu, Jiang, Xin, Xu, Long, Shen, Luyan, Yu, Huimei, Sun, Liankun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949157/
https://www.ncbi.nlm.nih.gov/pubmed/35328718
http://dx.doi.org/10.3390/ijms23063290

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