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The Efficacy of Fibrinogen Concentrates in Relation to Cryoprecipitate in Restoring Clot Integrity and Stability against Lysis

Loss of fibrinogen is a feature of trauma-induced coagulopathy (TIC), and restoring this clotting factor is protective against hemorrhages. We compared the efficacy of cryoprecipitate, and of the fibrinogen concentrates RiaSTAP(®) and FibCLOT(®) in restoring the clot integrity in models of TIC. Cryo...

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Detalles Bibliográficos
Autores principales: Whyte, Claire S., Rastogi, Akriti, Ferguson, Ellis, Donnarumma, Michela, Mutch, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949572/
https://www.ncbi.nlm.nih.gov/pubmed/35328366
http://dx.doi.org/10.3390/ijms23062944