Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group

BACKGROUND: In moderate-to-severe COVID-19 pneumonia, dexamethasone (DEX) and tocilizumab (TCZ) reduce the occurrence of death and ventilatory support. We investigated the efficacy and safety of DEX+TCZ in an open randomized clinical trial. METHODS: From July 24, 2020, through May 18, 2021, patients...

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Detalles Bibliográficos
Autores principales: Hermine, Olivier, Mariette, Xavier, Porcher, Raphael, Djossou, Felix, Nguyen, Yann, Arlet, Jean-Benoît, Savale, Laurent, Diehl, Jean Luc, Georgin-Lavialle, Sophie, Cadranel, Jacques, Pialoux, Gilles, Lacombe, Karine, Mekinian, Arsène, Gros, Hélène, Lescure, Xavier, Ghosn, Jade, Coupez, Elisabeth, Grapin, Kevin, Rapp, Christophe, Michel, Marc, Lecapitaine, Anne Lise, Michot, Jean Marie, Costedoat-Chalumeau, Nathalie, Nguyen, Liem Binh Luong, Semerano, Luca, Raffi, François, Aguillar, Claire, Rouzaud, Claire, Gottenberg, Jacques Eric, Hansmann, Yves, Bienvenu, Boris, London, Jonathan, Fantchou, Franklin Samou, Ackermann, Felix, Gros, Antoine, Morel, Alexandre, Gambier, Nicolas, Sène, Damien, Mégarbane, Bruno, Azoulay, Elie, Bureau, Serge, Dougados, Maxime, Emmerich, Joseph, Fartoukh, Muriel, Guidet, Bertrand, Humbert, Marc, Mahevas, Mathieu, Pène, Frédéric, Schlemmer, Frédéric, Pourcher-Martinez, Valérie, Tibi, Annick, Baron, Gabriel, Perrodeau, Elodie, Baron, Stéphanie, Steg, Gabriel, Yazdapanah, Yazdan, Simon, Tabassome, Resche-Rigon, Matthieu, Tharaux, Pierre-Louis, Ravaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949640/
https://www.ncbi.nlm.nih.gov/pubmed/35350097
http://dx.doi.org/10.1016/j.eclinm.2022.101362

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