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Automated Synthesis of (68)Ga-Labeled DOTA-MGS8 and Preclinical Characterization of Cholecystokinin-2 Receptor Targeting

The new minigastrin analog DOTA-MGS8 targeting the cholecystokinin-2 receptor (CCK2R) used in this study displays the combination of two site-specific modifications within the C-terminal receptor binding sequence together with an additional N-terminal amino acid substitution preventing fast metaboli...

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Detalles Bibliográficos
Autores principales: Hörmann, Anton Amadeus, Plhak, Elisabeth, Klingler, Maximilian, Rangger, Christine, Pfister, Joachim, Schwach, Gert, Kvaternik, Herbert, von Guggenberg, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949806/
https://www.ncbi.nlm.nih.gov/pubmed/35335396
http://dx.doi.org/10.3390/molecules27062034