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BMP-2 Long-Term Stimulation of Human Pre-Osteoblasts Induces Osteogenic Differentiation and Promotes Transdifferentiation and Bone Remodeling Processes
Bone morphogenic protein (BMP-) 2 plays an important role in the regeneration of bone defects by promoting osteogenic differentiation. However, several animal studies have reported adverse side effects of BMP-2, including osteoclast activation, induction of peroxisome proliferator- activated recepto...
Autores principales: | Ingwersen, Lena-Christin, Frank, Marcus, Naujokat, Hendrik, Loger, Klaas, Bader, Rainer, Jonitz-Heincke, Anika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949995/ https://www.ncbi.nlm.nih.gov/pubmed/35328498 http://dx.doi.org/10.3390/ijms23063077 |
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