Cargando…

HMGA2: A Biomarker in Gynecologic Neoplasia

High Mobility Group A2 gene (HMGA2), an oncofetal protein, is normally expressed in fetal development and completely shuts down in almost all organs and tissue types during adulthood. It is upregulated or overexpressed again in certain mesenchymal neoplasms due to chromosomal translocations and in m...

Descripción completa

Detalles Bibliográficos
Autor principal:	Wei, Jian-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950094/ https://www.ncbi.nlm.nih.gov/pubmed/35340777 http://dx.doi.org/10.14218/JCTP.2021.00018

Ejemplares similares

High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial Neoplasia
por: Unachukwu, Uchenna, et al.
Publicado: (2020)

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2
por: Tian, Xiaoxue, et al.
Publicado: (2020)

Emerging roles for HMGA2 in colorectal cancer
por: Wang, Xin, et al.
Publicado: (2020)

HMGA1 and HMGA2 expression and comparative analyses of HMGA2, Lin28 and let-7 miRNAs in oral squamous cell carcinoma
por: Sterenczak, Katharina Anna, et al.
Publicado: (2014)

Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
por: Federico, Antonella, et al.
Publicado: (2014)

Effect and mechanism of circHMGA2 on ferroptosis and pyroptosis in myocardial ischemia-reperfusion model CircHMGA2 exacerbates MI/R injury
por: Feng, Pin, et al.
Publicado: (2023)

The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3′UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2
por: Wang, Yuan, et al.
Publicado: (2017)

HMGA2 promotes the migration and invasion of gallbladder cancer cells and HMGA2 knockdown inhibits angiogenesis via targeting VEGFA
por: Yan, Jun, et al.
Publicado: (2022)

HMGA1 As a Potential Prognostic and Therapeutic Biomarker in Breast Cancer
por: Wang, Tian, et al.
Publicado: (2022)

Let-7 repression leads to HMGA2 overexpression in uterine leiomyosarcoma
por: Shi, Guizhi, et al.
Publicado: (2009)

Proteomic analysis identifies HMGA2 as a novel biomarker of overall survival in papillary renal cell carcinoma
por: Wei, Tian, et al.
Publicado: (2023)

TGF-β1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion
por: Zhong, Jing, et al.
Publicado: (2017)

Hmga2 translocation induced in skin tumorigenesis
por: Li, Yong, et al.
Publicado: (2017)

Prognostic significance of high mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: malignant functions of cytoplasmic HMGA2 expression
por: Gundlach, Jan-Paul, et al.
Publicado: (2021)

HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion
por: Ros, Gloria, et al.
Publicado: (2020)

HMGA2 Expression in Renal Carcinoma and its Clinical Significance
por: Liu, Ying, et al.
Publicado: (2015)

An open or closed case for HMGA
por: Williams, Ruth
Publicado: (2006)

HMGA1-pseudogenes and cancer
por: De Martino, Marco, et al.
Publicado: (2016)

HMGA Proteins in Hematological Malignancies
por: Minervini, Angela, et al.
Publicado: (2020)

MED12 and HMGA2 mutations: Two independent genetic events in uterine leiomyoma and leiomyosarcoma
por: Bertsch, Elizabeth, et al.
Publicado: (2014)

HMGA2 as a Critical Regulator in Cancer Development
por: Mansoori, Behzad, et al.
Publicado: (2021)

HMGA2 regulates lung cancer proliferation and metastasis
por: Gao, Xiaotian, et al.
Publicado: (2017)

A polymorphism of HMGA1 protects against proliferative diabetic retinopathy by impairing HMGA1-induced VEGFA expression
por: Chiefari, Eusebio, et al.
Publicado: (2016)

Rearrangement of chromosome bands 12q14~15 causing HMGA2-SOX5 gene fusion and HMGA2 expression in extraskeletal osteochondroma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

HMGA2 expression pattern and TERT mutations in tumors of the vulva
por: AGOSTINI, ANTONIO, et al.
Publicado: (2015)

Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomas
por: Pareja, Fresia, et al.
Publicado: (2019)

Oncofetal HMGA2 effectively curbs unconstrained (+) and (−) DNA supercoiling
por: Zhao, Xiaodan, et al.
Publicado: (2017)

HMGA Genes and Proteins in Development and Evolution
por: Vignali, Robert, et al.
Publicado: (2020)

Chromatin Immunoprecipitation to Analyze DNA Binding Sites of HMGA2
por: Winter, Nina, et al.
Publicado: (2011)

Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women()
por: Jiang, Yunhui, et al.
Publicado: (2019)

Characterization of the Stoichiometry of HMGA1/DNA Complexes
por: Watanabe, Miki, et al.
Publicado: (2013)

Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
por: Ouchi, Kazutaka, et al.
Publicado: (2020)

Association of HMGA2 Polymorphisms with Glioma Susceptibility in Chinese Children
por: Zhou, Jingying, et al.
Publicado: (2021)

Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia
por: Suh, Han Na, et al.
Publicado: (2016)

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance
por: Chiou, Shin-Heng, et al.
Publicado: (2018)

HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer
por: Mansoori, Behzad, et al.
Publicado: (2021)

Corrigendum to “HMGA1 expression in human hepatocellular carcinoma correlates with poor prognosis and promotes tumor growth and migration in in vitro models” [Neoplasia 18 (2016) 724–731]()
por: Andreozzi, Mariacarla, et al.
Publicado: (2020)

Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma
por: Chang, Kai-Ping, et al.
Publicado: (2015)

Hmga2 is required for canonical WNT signaling during lung development
por: Singh, Indrabahadur, et al.
Publicado: (2014)

RNA-Mediated Regulation of HMGA1 Function
por: Benecke, Arndt G., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uiagefnf96pbtqaeparmf9b26f