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On the Efficacy of ZnO Nanostructures against SARS-CoV-2
In 2019, the new coronavirus disease (COVID-19), related to the severe acute respiratory syndrome coronavirus (SARS-CoV-2), started spreading around the word, giving rise to the world pandemic we are still facing. Since then, many strategies for the prevention and control of COVID-19 have been studi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950216/ https://www.ncbi.nlm.nih.gov/pubmed/35328455 http://dx.doi.org/10.3390/ijms23063040 |
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author | Sportelli, Maria Chiara Izzi, Margherita Loconsole, Daniela Sallustio, Anna Picca, Rosaria Anna Felici, Roberto Chironna, Maria Cioffi, Nicola |
author_facet | Sportelli, Maria Chiara Izzi, Margherita Loconsole, Daniela Sallustio, Anna Picca, Rosaria Anna Felici, Roberto Chironna, Maria Cioffi, Nicola |
author_sort | Sportelli, Maria Chiara |
collection | PubMed |
description | In 2019, the new coronavirus disease (COVID-19), related to the severe acute respiratory syndrome coronavirus (SARS-CoV-2), started spreading around the word, giving rise to the world pandemic we are still facing. Since then, many strategies for the prevention and control of COVID-19 have been studied and implemented. In addition to pharmacological treatments and vaccines, it is mandatory to ensure the cleaning and disinfection of the skin and inanimate surfaces, especially in those contexts where the contagion could spread quickly, such as hospitals and clinical laboratories, schools, transport, and public places in general. Here, we report the efficacy of ZnO nanoparticles (ZnONPs) against SARS-CoV-2. NPs were produced using an ecofriendly method and fully characterized; their antiviral activity was tested in vitro against SARS-CoV-2, showing a decrease in viral load between 70% and 90%, as a function of the material’s composition. Application of these nano-antimicrobials as coatings for commonly touched surfaces is envisaged. |
format | Online Article Text |
id | pubmed-8950216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89502162022-03-26 On the Efficacy of ZnO Nanostructures against SARS-CoV-2 Sportelli, Maria Chiara Izzi, Margherita Loconsole, Daniela Sallustio, Anna Picca, Rosaria Anna Felici, Roberto Chironna, Maria Cioffi, Nicola Int J Mol Sci Article In 2019, the new coronavirus disease (COVID-19), related to the severe acute respiratory syndrome coronavirus (SARS-CoV-2), started spreading around the word, giving rise to the world pandemic we are still facing. Since then, many strategies for the prevention and control of COVID-19 have been studied and implemented. In addition to pharmacological treatments and vaccines, it is mandatory to ensure the cleaning and disinfection of the skin and inanimate surfaces, especially in those contexts where the contagion could spread quickly, such as hospitals and clinical laboratories, schools, transport, and public places in general. Here, we report the efficacy of ZnO nanoparticles (ZnONPs) against SARS-CoV-2. NPs were produced using an ecofriendly method and fully characterized; their antiviral activity was tested in vitro against SARS-CoV-2, showing a decrease in viral load between 70% and 90%, as a function of the material’s composition. Application of these nano-antimicrobials as coatings for commonly touched surfaces is envisaged. MDPI 2022-03-11 /pmc/articles/PMC8950216/ /pubmed/35328455 http://dx.doi.org/10.3390/ijms23063040 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sportelli, Maria Chiara Izzi, Margherita Loconsole, Daniela Sallustio, Anna Picca, Rosaria Anna Felici, Roberto Chironna, Maria Cioffi, Nicola On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title | On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title_full | On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title_fullStr | On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title_full_unstemmed | On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title_short | On the Efficacy of ZnO Nanostructures against SARS-CoV-2 |
title_sort | on the efficacy of zno nanostructures against sars-cov-2 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950216/ https://www.ncbi.nlm.nih.gov/pubmed/35328455 http://dx.doi.org/10.3390/ijms23063040 |
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