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Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase—A Potential Drug Delivery System

Phenylketonuria (PKU) is an autosomal recessive disease caused by deficient activity of human phenylalanine hydroxylase (hPAH), which can lead to neurologic impairments in untreated patients. Although some therapies are already available for PKU, these are not without drawbacks. Enzyme-replacement t...

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Detalles Bibliográficos
Autores principales: Alves, Márcia M. S., Leandro, Paula, Mertens, Haydyn D. T., Pereiro, Ana B., Archer, Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950220/
https://www.ncbi.nlm.nih.gov/pubmed/35335706
http://dx.doi.org/10.3390/nano12060893

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