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Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase—A Potential Drug Delivery System
Phenylketonuria (PKU) is an autosomal recessive disease caused by deficient activity of human phenylalanine hydroxylase (hPAH), which can lead to neurologic impairments in untreated patients. Although some therapies are already available for PKU, these are not without drawbacks. Enzyme-replacement t...
Autores principales: | Alves, Márcia M. S., Leandro, Paula, Mertens, Haydyn D. T., Pereiro, Ana B., Archer, Margarida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950220/ https://www.ncbi.nlm.nih.gov/pubmed/35335706 http://dx.doi.org/10.3390/nano12060893 |
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