Cargando…
Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses
Changes in cellular metabolism have been implicated in mediating the activated fibroblast phenotype in a number of chronic inflammatory disorders, including pulmonary fibrosis, renal disease and rheumatoid arthritis. The aim of this study was therefore to characterise the metabolic profile of synovi...
Autores principales: | Farah, Hussein, Wijesinghe, Susanne N., Nicholson, Thomas, Alnajjar, Fawzeyah, Certo, Michelangelo, Alghamdi, Abdullah, Davis, Edward T., Young, Stephen P., Mauro, Claudio, Jones, Simon W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950319/ https://www.ncbi.nlm.nih.gov/pubmed/35328687 http://dx.doi.org/10.3390/ijms23063266 |
Ejemplares similares
-
Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets
por: Wijesinghe, Susanne N., et al.
Publicado: (2023) -
The Expression and Function of Metastases Associated Lung Adenocarcinoma Transcript-1 Long Non-Coding RNA in Subchondral Bone and Osteoblasts from Patients with Osteoarthritis
por: Alnajjar, Fawzeyah A., et al.
Publicado: (2021) -
Proteomic analysis of human osteoarthritis synovial fluid
por: Balakrishnan, Lavanya, et al.
Publicado: (2014) -
Serum and synovial fluid cytokine profiling in hip osteoarthritis: distinct from knee osteoarthritis and correlated with pain
por: Ren, Guomin, et al.
Publicado: (2018) -
Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets
por: Nanus, Dominika E, et al.
Publicado: (2021)