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Polymer Translocation through Nanometer Pores

In this paper the loaded polymer transport and its escape via a nanometer size aperture, virtually by nanomembrane, the polymer being moved by an exterior electrostatic field, has been studied. Assuming a linear dependency of the friction coefficient on the number of segments m and a parabolic behav...

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Detalles Bibliográficos
Autores principales: Paun, Maria-Alexandra, Paun, Vladimir-Alexandru, Paun, Viorel-Puiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950326/
https://www.ncbi.nlm.nih.gov/pubmed/35335497
http://dx.doi.org/10.3390/polym14061166
Descripción
Sumario:In this paper the loaded polymer transport and its escape via a nanometer size aperture, virtually by nanomembrane, the polymer being moved by an exterior electrostatic field, has been studied. Assuming a linear dependency of the friction coefficient on the number of segments m and a parabolic behavior for the open-free (Gibbs) energy, in attendance of a present electrical potential across nanopore, an explicit flux formula for the polymers passed over a dimensional restricted pore, was derived. In addition, the linear polymers transport through a nanometer-sized pore under the action of a constant force is presented. The important mechanical effects of superimposed steady force and the monomers number of macromolecule chain on the polymer translocation process by nanomembranes, in a 2D diffusion model, have been demonstrated. The escape time by a three-dimensional graph as a function of the electric field intensity and monomers number of polymer was represented.