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Polymer Translocation through Nanometer Pores
In this paper the loaded polymer transport and its escape via a nanometer size aperture, virtually by nanomembrane, the polymer being moved by an exterior electrostatic field, has been studied. Assuming a linear dependency of the friction coefficient on the number of segments m and a parabolic behav...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950326/ https://www.ncbi.nlm.nih.gov/pubmed/35335497 http://dx.doi.org/10.3390/polym14061166 |
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author | Paun, Maria-Alexandra Paun, Vladimir-Alexandru Paun, Viorel-Puiu |
author_facet | Paun, Maria-Alexandra Paun, Vladimir-Alexandru Paun, Viorel-Puiu |
author_sort | Paun, Maria-Alexandra |
collection | PubMed |
description | In this paper the loaded polymer transport and its escape via a nanometer size aperture, virtually by nanomembrane, the polymer being moved by an exterior electrostatic field, has been studied. Assuming a linear dependency of the friction coefficient on the number of segments m and a parabolic behavior for the open-free (Gibbs) energy, in attendance of a present electrical potential across nanopore, an explicit flux formula for the polymers passed over a dimensional restricted pore, was derived. In addition, the linear polymers transport through a nanometer-sized pore under the action of a constant force is presented. The important mechanical effects of superimposed steady force and the monomers number of macromolecule chain on the polymer translocation process by nanomembranes, in a 2D diffusion model, have been demonstrated. The escape time by a three-dimensional graph as a function of the electric field intensity and monomers number of polymer was represented. |
format | Online Article Text |
id | pubmed-8950326 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89503262022-03-26 Polymer Translocation through Nanometer Pores Paun, Maria-Alexandra Paun, Vladimir-Alexandru Paun, Viorel-Puiu Polymers (Basel) Review In this paper the loaded polymer transport and its escape via a nanometer size aperture, virtually by nanomembrane, the polymer being moved by an exterior electrostatic field, has been studied. Assuming a linear dependency of the friction coefficient on the number of segments m and a parabolic behavior for the open-free (Gibbs) energy, in attendance of a present electrical potential across nanopore, an explicit flux formula for the polymers passed over a dimensional restricted pore, was derived. In addition, the linear polymers transport through a nanometer-sized pore under the action of a constant force is presented. The important mechanical effects of superimposed steady force and the monomers number of macromolecule chain on the polymer translocation process by nanomembranes, in a 2D diffusion model, have been demonstrated. The escape time by a three-dimensional graph as a function of the electric field intensity and monomers number of polymer was represented. MDPI 2022-03-15 /pmc/articles/PMC8950326/ /pubmed/35335497 http://dx.doi.org/10.3390/polym14061166 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Paun, Maria-Alexandra Paun, Vladimir-Alexandru Paun, Viorel-Puiu Polymer Translocation through Nanometer Pores |
title | Polymer Translocation through Nanometer Pores |
title_full | Polymer Translocation through Nanometer Pores |
title_fullStr | Polymer Translocation through Nanometer Pores |
title_full_unstemmed | Polymer Translocation through Nanometer Pores |
title_short | Polymer Translocation through Nanometer Pores |
title_sort | polymer translocation through nanometer pores |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950326/ https://www.ncbi.nlm.nih.gov/pubmed/35335497 http://dx.doi.org/10.3390/polym14061166 |
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