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Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19
A 48-year-old female patient underwent a heart transplantation for acute fulminant myocarditis, following heterologous vaccination with the ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19. She had no history of severe acute respiratory syndrome coronavirus-2 infection. She did not exhibit clinical sign...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950462/ https://www.ncbi.nlm.nih.gov/pubmed/35334625 http://dx.doi.org/10.3390/medicina58030449 |
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author | Kang, Dong-Hoon Na, Joo-Young Yang, Jun-Ho Moon, Seong-Ho Kim, Sung-Hwan Jung, Jae-Jun Cha, Ho-Jeong Ahn, Jong-Hwa Park, Yong-Whi Cho, Sang-Yeong Yu, Ho-Kyung Lee, Soo-Hee Park, Mi-Yeong Kim, Jong-Woo Byun, Joung-Hun |
author_facet | Kang, Dong-Hoon Na, Joo-Young Yang, Jun-Ho Moon, Seong-Ho Kim, Sung-Hwan Jung, Jae-Jun Cha, Ho-Jeong Ahn, Jong-Hwa Park, Yong-Whi Cho, Sang-Yeong Yu, Ho-Kyung Lee, Soo-Hee Park, Mi-Yeong Kim, Jong-Woo Byun, Joung-Hun |
author_sort | Kang, Dong-Hoon |
collection | PubMed |
description | A 48-year-old female patient underwent a heart transplantation for acute fulminant myocarditis, following heterologous vaccination with the ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19. She had no history of severe acute respiratory syndrome coronavirus-2 infection. She did not exhibit clinical signs or have laboratory findings of concomitant infection before or after vaccination. Heart transplantation was performed because her heart failed to recover with venoarterial extracorporeal oxygenation support. Organ autopsy revealed giant cell myocarditis, possibly related to the vaccines. Clinicians may have to consider the possibility of the development of giant cell myocarditis, especially in patients with rapidly deteriorating cardiac function and myocarditis symptoms after COVID-19 vaccination. |
format | Online Article Text |
id | pubmed-8950462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89504622022-03-26 Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 Kang, Dong-Hoon Na, Joo-Young Yang, Jun-Ho Moon, Seong-Ho Kim, Sung-Hwan Jung, Jae-Jun Cha, Ho-Jeong Ahn, Jong-Hwa Park, Yong-Whi Cho, Sang-Yeong Yu, Ho-Kyung Lee, Soo-Hee Park, Mi-Yeong Kim, Jong-Woo Byun, Joung-Hun Medicina (Kaunas) Case Report A 48-year-old female patient underwent a heart transplantation for acute fulminant myocarditis, following heterologous vaccination with the ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19. She had no history of severe acute respiratory syndrome coronavirus-2 infection. She did not exhibit clinical signs or have laboratory findings of concomitant infection before or after vaccination. Heart transplantation was performed because her heart failed to recover with venoarterial extracorporeal oxygenation support. Organ autopsy revealed giant cell myocarditis, possibly related to the vaccines. Clinicians may have to consider the possibility of the development of giant cell myocarditis, especially in patients with rapidly deteriorating cardiac function and myocarditis symptoms after COVID-19 vaccination. MDPI 2022-03-20 /pmc/articles/PMC8950462/ /pubmed/35334625 http://dx.doi.org/10.3390/medicina58030449 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Kang, Dong-Hoon Na, Joo-Young Yang, Jun-Ho Moon, Seong-Ho Kim, Sung-Hwan Jung, Jae-Jun Cha, Ho-Jeong Ahn, Jong-Hwa Park, Yong-Whi Cho, Sang-Yeong Yu, Ho-Kyung Lee, Soo-Hee Park, Mi-Yeong Kim, Jong-Woo Byun, Joung-Hun Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title | Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title_full | Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title_fullStr | Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title_full_unstemmed | Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title_short | Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19 |
title_sort | fulminant giant cell myocarditis following heterologous vaccination of chadox1 ncov-19 and pfizer-biontech covid-19 |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950462/ https://www.ncbi.nlm.nih.gov/pubmed/35334625 http://dx.doi.org/10.3390/medicina58030449 |
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