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A pH- and Bioreducible Cationic Copolymer with Amino Acids and Piperazines for Adenovirus Delivery

Adenoviruses (Ads) are attractive nonviral vectors and show great potential in cancer gene therapy. However, inherent properties of Ads, including immunogenicity, nonspecific toxicity, and coxsackie and adenovirus receptor (CAR)-dependent cell uptake, limit their clinical use. To surmount these issu...

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Detalles Bibliográficos
Autores principales:	Thambi, Thavasyappan, Lee, Jeongmin, Yoon, A-Rum, Kasala, Dayananda, Yun, Chae-Ok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950541/ https://www.ncbi.nlm.nih.gov/pubmed/35335972 http://dx.doi.org/10.3390/pharmaceutics14030597

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