Trehalose Activates Hepatic and Myocardial Autophagy and Has Anti-Inflammatory Effects in db/db Diabetic Mice

Db/db mice (carrying a mutation in the gene encoding leptin receptor) show autophagy suppression. Our aim was to evaluate the effect of autophagy inducer trehalose on liver and heart autophagy in db/db mice and to study inflammation dysregulation and the suitability of chitinases’ expression levels...

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Detalles Bibliográficos
Autores principales: Korolenko, Tatiana A., Ovsyukova, Marina V., Bgatova, Nataliya P., Ivanov, Igor D., Makarova, Svetlana I., Vavilin, Valentin A., Popov, Alexey V., Yuzhik, Ekaterina I., Koldysheva, Elena V., Korolenko, Erik C., Zavjalov, Evgeny L., Amstislavskaya, Tamara G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950581/
https://www.ncbi.nlm.nih.gov/pubmed/35330193
http://dx.doi.org/10.3390/life12030442

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