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Clonal Selection and Evolution of HTLV-1-Infected Cells Driven by Genetic and Epigenetic Alteration

T cells infected with human T-cell leukemia virus type 1 (HTLV-1) acquire various abnormalities during a long latent period and transform into highly malignant adult T-cell leukemia-lymphoma (ATL) cells. This can be described as “clonal evolution”, in which a single clone evolves into ATL cells afte...

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Detalles Bibliográficos
Autores principales:	Yamagishi, Makoto, Suzuki, Yutaka, Watanabe, Toshiki, Uchimaru, Kaoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950914/ https://www.ncbi.nlm.nih.gov/pubmed/35336993 http://dx.doi.org/10.3390/v14030587

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