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Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk

Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2, loop 4) and brain-derived neurotrophic factor, BDNF (GSB-214,...

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Detalles Bibliográficos
Autores principales:	Mezhlumyan, Armen G., Tallerova, Anna V., Povarnina, Polina Y., Tarasiuk, Aleksey V., Sazonova, Nellya M., Gudasheva, Tatiana A., Seredenin, Sergey B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950955/ https://www.ncbi.nlm.nih.gov/pubmed/35337082 http://dx.doi.org/10.3390/ph15030284

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