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Effect of Caffeine and Flavonoids on the Binding of Tigecycline to Human Serum Albumin: A Spectroscopic Study and Molecular Docking
Human serum albumin (HSA) has a very significant role in the transport of drugs, in their pharmacokinetic and pharmacodynamic properties, as well as the unbound concentration of drugs in circulating plasma. The aim of this study was to look into the competition between tigecycline (TGC) and alkaloid...
Autores principales: | Sovrlić, Miroslav, Mrkalić, Emina, Jelić, Ratomir, Ćendić Serafinović, Marina, Stojanović, Stefan, Prodanović, Nevena, Tomović, Jovica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951011/ https://www.ncbi.nlm.nih.gov/pubmed/35337065 http://dx.doi.org/10.3390/ph15030266 |
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