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Effect of Trehalose and Ceftriaxone on the Stability of Aggregating-Prone Tau Peptide Containing PHF6* Sequence: An SRCD Study

The tau protein, a soluble protein associated with microtubules, which is involved in the assembly and stabilization of cytoskeletal elements, was found to form neurofibrillary tangles in different neurodegenerative diseases. Insoluble tau aggregates were observed to be organized in paired helical f...

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Detalles Bibliográficos
Autores principales: Honisch, Claudia, Torni, Federica, Hussain, Rohanah, Ruzza, Paolo, Siligardi, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951053/
https://www.ncbi.nlm.nih.gov/pubmed/35328353
http://dx.doi.org/10.3390/ijms23062932