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Calculation of Permeability Coefficients from Solute Equilibration Dynamics: An Assessment of Various Methods

Predicting the rate at which substances permeate membrane barriers in vivo is crucial for drug development. Permeability coefficients obtained from in vitro studies are valuable for this goal. These are normally determined by following the dynamics of solute equilibration between two membrane-separa...

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Detalles Bibliográficos
Autores principales: Cordeiro, Margarida M., Salvador, Armindo, Moreno, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951150/
https://www.ncbi.nlm.nih.gov/pubmed/35323728
http://dx.doi.org/10.3390/membranes12030254