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Calculation of Permeability Coefficients from Solute Equilibration Dynamics: An Assessment of Various Methods
Predicting the rate at which substances permeate membrane barriers in vivo is crucial for drug development. Permeability coefficients obtained from in vitro studies are valuable for this goal. These are normally determined by following the dynamics of solute equilibration between two membrane-separa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951150/ https://www.ncbi.nlm.nih.gov/pubmed/35323728 http://dx.doi.org/10.3390/membranes12030254 |