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Poly-l-lysine-caused cell adhesion induces pyroptosis in THP-1 monocytes

Pyroptosis is a kind of cell necrosis mediated by inflammasomes. The caspase 1-induced cleavage of gasdermin D (GSDMD) is a canonical pathway to cause membrane pores and eventually cell pyroptosis. Poly-l-lysine (PLL) is widely used to enhance cell adhesion during experiments. Human THP-1 cells are...

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Detalles Bibliográficos
Autores principales: Yu, Chaoping, Zhao, Wei, Duan, Chujun, Xie, Jiangang, Yin, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951213/
https://www.ncbi.nlm.nih.gov/pubmed/35415237
http://dx.doi.org/10.1515/biol-2022-0028

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