Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence

Living donor kidney transplantation is a widely performed medical procedure. Living kidney donation requires an in-depth health assessment of candidates. The potential living kidney donor must remain healthy after kidney removal. A consequence of donation can be a decrease in glomerular filtration r...

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Autores principales: Poznański, Paweł, Lepiesza, Agnieszka, Jędrzejuk, Diana, Mazanowska, Oktawia, Bolanowski, Marek, Krajewska, Magdalena, Kamińska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951425/
https://www.ncbi.nlm.nih.gov/pubmed/35329811
http://dx.doi.org/10.3390/jcm11061485
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author Poznański, Paweł
Lepiesza, Agnieszka
Jędrzejuk, Diana
Mazanowska, Oktawia
Bolanowski, Marek
Krajewska, Magdalena
Kamińska, Dorota
author_facet Poznański, Paweł
Lepiesza, Agnieszka
Jędrzejuk, Diana
Mazanowska, Oktawia
Bolanowski, Marek
Krajewska, Magdalena
Kamińska, Dorota
author_sort Poznański, Paweł
collection PubMed
description Living donor kidney transplantation is a widely performed medical procedure. Living kidney donation requires an in-depth health assessment of candidates. The potential living kidney donor must remain healthy after kidney removal. A consequence of donation can be a decrease in glomerular filtration rate (GFR), and donors can become at risk of developing chronic kidney disease (CKD). We present a rationale for potential living kidney donor withdrawal due to Paget’s disease of bone (PDB) based on a literature review. The treatment for PDB includes the use of, for example, non-steroidal anti-inflammatory drugs (NSAIDs), which can lead to acute kidney injury (AKI) as well as CKD, or bisphosphonates, which are not recommended for patients with decreased GFR.
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spelling pubmed-89514252022-03-26 Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence Poznański, Paweł Lepiesza, Agnieszka Jędrzejuk, Diana Mazanowska, Oktawia Bolanowski, Marek Krajewska, Magdalena Kamińska, Dorota J Clin Med Review Living donor kidney transplantation is a widely performed medical procedure. Living kidney donation requires an in-depth health assessment of candidates. The potential living kidney donor must remain healthy after kidney removal. A consequence of donation can be a decrease in glomerular filtration rate (GFR), and donors can become at risk of developing chronic kidney disease (CKD). We present a rationale for potential living kidney donor withdrawal due to Paget’s disease of bone (PDB) based on a literature review. The treatment for PDB includes the use of, for example, non-steroidal anti-inflammatory drugs (NSAIDs), which can lead to acute kidney injury (AKI) as well as CKD, or bisphosphonates, which are not recommended for patients with decreased GFR. MDPI 2022-03-09 /pmc/articles/PMC8951425/ /pubmed/35329811 http://dx.doi.org/10.3390/jcm11061485 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Poznański, Paweł
Lepiesza, Agnieszka
Jędrzejuk, Diana
Mazanowska, Oktawia
Bolanowski, Marek
Krajewska, Magdalena
Kamińska, Dorota
Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title_full Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title_fullStr Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title_full_unstemmed Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title_short Is a Patient with Paget’s Disease of Bone Suitable for Living Kidney Donation?—Decision-Making in Lack of Clinical Evidence
title_sort is a patient with paget’s disease of bone suitable for living kidney donation?—decision-making in lack of clinical evidence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951425/
https://www.ncbi.nlm.nih.gov/pubmed/35329811
http://dx.doi.org/10.3390/jcm11061485
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