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Determination of Methyl Methanesulfonate and Ethyl Methylsulfonate in New Drug for the Treatment of Fatty Liver Using Derivatization Followed by High-Performance Liquid Chromatography with Ultraviolet Detection

A new derivatization high-performance liquid chromatography method with ultraviolet detection was developed and validated for the quantitative analysis of methanesulfonate genotoxic impurities in an innovative drug for the treatment of non-alcoholic fatty liver disease. In this study, sodium dibenzy...

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Detalles Bibliográficos
Autores principales:	Wang, Yue, Feng, Jing, Wu, Song, Shao, Huihui, Zhang, Wenxuan, Zhang, Kun, Zhang, Hanyilan, Yang, Qingyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951586/ https://www.ncbi.nlm.nih.gov/pubmed/35335314 http://dx.doi.org/10.3390/molecules27061950

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