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Electromagnetic Force-Driven Needle-Free in Ovo Injection Device

Needle-free injections are mainly used for administering human or mammalian vaccines or drugs. However, poultry vaccines, in ovo injections to embryos, subcutaneous injections to chickens, and intramuscular injections are administered using needle injections. This article presents a new needle-free...

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Autores principales: Huang, Ko-Jung, Li, Cheng-Han, Tsai, Ping-Kun, Lai, Chia-Chun, Kuo, Yu-Ren, Hsieh, Ming-Kun, Cheng, Ching-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951732/
https://www.ncbi.nlm.nih.gov/pubmed/35324876
http://dx.doi.org/10.3390/vetsci9030147
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author Huang, Ko-Jung
Li, Cheng-Han
Tsai, Ping-Kun
Lai, Chia-Chun
Kuo, Yu-Ren
Hsieh, Ming-Kun
Cheng, Ching-Wei
author_facet Huang, Ko-Jung
Li, Cheng-Han
Tsai, Ping-Kun
Lai, Chia-Chun
Kuo, Yu-Ren
Hsieh, Ming-Kun
Cheng, Ching-Wei
author_sort Huang, Ko-Jung
collection PubMed
description Needle-free injections are mainly used for administering human or mammalian vaccines or drugs. However, poultry vaccines, in ovo injections to embryos, subcutaneous injections to chickens, and intramuscular injections are administered using needle injections. This article presents a new needle-free in ovo injection device method that uses push-pull solenoids to eject liquid jets, mainly for embryonic eggs of chickens. Furthermore, our study investigated the suitable jet pressures for using this method and the post-injection hatching rates in 18-day-old embryonic eggs. Using this method, we could deliver the liquid to the allantoic and amniotic cavities or the muscle tissue through the egg membrane of the air chamber using a jet pressure of ~6–7 MPa or ~8 MPa. After injecting 0.25 mL of 0.9% saline into 18-day-old Lohmann breed layer embryonic eggs and specific pathogen-free (SPF) embryonic eggs at a jet pressure of ~7 MPa, we observed hatching rates of 98.3% and 85.7%, respectively. This study’s electromagnetic needle-free in ovo injection device can apply vaccine or nutrient solution injection for embryo eggs and serve as a reference for future studies on needle-free in ovo injection automation systems, jet pressure control, and injection pretreatment processes.
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spelling pubmed-89517322022-03-26 Electromagnetic Force-Driven Needle-Free in Ovo Injection Device Huang, Ko-Jung Li, Cheng-Han Tsai, Ping-Kun Lai, Chia-Chun Kuo, Yu-Ren Hsieh, Ming-Kun Cheng, Ching-Wei Vet Sci Article Needle-free injections are mainly used for administering human or mammalian vaccines or drugs. However, poultry vaccines, in ovo injections to embryos, subcutaneous injections to chickens, and intramuscular injections are administered using needle injections. This article presents a new needle-free in ovo injection device method that uses push-pull solenoids to eject liquid jets, mainly for embryonic eggs of chickens. Furthermore, our study investigated the suitable jet pressures for using this method and the post-injection hatching rates in 18-day-old embryonic eggs. Using this method, we could deliver the liquid to the allantoic and amniotic cavities or the muscle tissue through the egg membrane of the air chamber using a jet pressure of ~6–7 MPa or ~8 MPa. After injecting 0.25 mL of 0.9% saline into 18-day-old Lohmann breed layer embryonic eggs and specific pathogen-free (SPF) embryonic eggs at a jet pressure of ~7 MPa, we observed hatching rates of 98.3% and 85.7%, respectively. This study’s electromagnetic needle-free in ovo injection device can apply vaccine or nutrient solution injection for embryo eggs and serve as a reference for future studies on needle-free in ovo injection automation systems, jet pressure control, and injection pretreatment processes. MDPI 2022-03-21 /pmc/articles/PMC8951732/ /pubmed/35324876 http://dx.doi.org/10.3390/vetsci9030147 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Huang, Ko-Jung
Li, Cheng-Han
Tsai, Ping-Kun
Lai, Chia-Chun
Kuo, Yu-Ren
Hsieh, Ming-Kun
Cheng, Ching-Wei
Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title_full Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title_fullStr Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title_full_unstemmed Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title_short Electromagnetic Force-Driven Needle-Free in Ovo Injection Device
title_sort electromagnetic force-driven needle-free in ovo injection device
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951732/
https://www.ncbi.nlm.nih.gov/pubmed/35324876
http://dx.doi.org/10.3390/vetsci9030147
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